The "Motoric Cognitive Risk" Syndrome in the Canadian Population: Analysis of Baseline Assessment of the Canadian Longitudinal Study on Aging (CLSA)
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,461
- 试验地点
- 1
- 主要终点
- Cardio-vascular risk factors and diseases assessed using reported health condition
研究概览
简要总结
Cognition and locomotion are two human abilities controlled by the brain. Their decline is highly prevalent with aging, and is greater than the simple sum of their respective prevalence, suggesting a complex age-related interplay between cognition and locomotion. Recently, a systematic review and meta-analysis has provided evidence that poor gait performance predicts dementia and, in particular, has demonstrated that "motoric cognitive risk" (MCR) syndrome, which has been described in cognitively healthy individuals and combines subjective cognitive complaint with objective slow gait speed, is a pre-dementia syndrome. The uniqueness of "motoric cognitive risk" (MCR)syndrome is that it does not rely on a complex evaluation or laboratory investigations. Thus, it is easy to apply in population-based settings. The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, in the Quebec population using the database of the NuAge study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals eligible for this study will be participants of the NuAge study
排除标准
- •Individuals not eligible for the NuAge study
- •mobility disability
- •no information about cognitive complaint
- •no measure of walking speed
结局指标
主要结局
Cardio-vascular risk factors and diseases assessed using reported health condition
时间窗: 1 day
medical history
次要结局
- Cardio-vascular risk factors and diseases assessed using physical examination: BMI(1 day)
- Cardio-vascular risk factors and diseases assessed using physical examination: HW ratio(1 day)
- Disability and functional limitations(12 months)
- Cognitive performance(1 day)
- physical and mental health(1 day)
- Physical performance(1 day)
- Cardio-vascular risk factors and diseases assessed using physical examination: blood pressure(1 day)
- Depression(1 day)
研究者
Olivier Beauchet
Professor of Geriatrics
Jewish General Hospital