Functional Magnetic Resonance Imaging in Deep Brain Stimulation

Universitaire Ziekenhuizen KU Leuven1 site in 1 country20 target enrollmentMarch 24, 2017

ConditionsEpilepsy Chronic Pain

Overview

Phase: N/A
Intervention: Not specified
Conditions: Epilepsy
Sponsor: Universitaire Ziekenhuizen KU Leuven
Enrollment: 20
Locations: 1
Primary Endpoint: Determine the functional networks that are involved in DBS
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

With fMRI, we want to understand the mechanisms of brain neuromodulation in (dys)functional brain circuits, to obtain knowledge on involved brain networks in DBS.

Detailed Description

Deep brain stimulation represents a neurosurgical treatment option for specific refractory neurological and psychiatric disorders. In these patients a specific brain target is stimulated through an electrode with the use of an implantable pulse generator (IPG). In a functional MRI (fMRI) experiment, the investigators intend to perform imaging during stimulation ON and compare brain activations with the stimulation OFF condition. In this way, they aim to elucidate the involved brain network in deep brain stimulation. Since the connectivity of deep brain structures is complex, different activation patterns are expected in-between subjects and conditions. If specific activation patterns during the stimulation ON condition can be related to treatment response, this is of important clinical value. These findings can lead to an optimization of the deep brain target or even to different useful targets for brain stimulation.

Registry

clinicaltrials.gov

Start Date

March 24, 2017

End Date

January 10, 2025

Last Updated

last year

Study Type

Interventional

Study Design

Single Group