Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer

Recruiting

• Conditions: Thyroid Cancer

• Registration Number: NCT05752604
• Lead Sponsor: Istituto Auxologico Italiano

Brief Summary

DTC has a generally favorable prognosis. The possibility to discriminate between patients with aggressive tumors and those with a more indolent behavior may reduce the need for unnecessary treatments. Aim of this observational study is to evaluate how anamnestic, clinical, and histopathological variables may influence the outcome of the enrolled patients, both regarding morbidity and mortality and in terms of therapeutic choices. The study aims to evaluate the prognostic impact of the therapeutic interventions in terms of efficacy and regarding the appearance of adverse events.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-12
• Study First Submitted: 2023-02-17
• Study First Submitted QC: 2023-03-01
• Study First Posted: 2023-03-02
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-15
• Last Update Posted: 2024-04-16
• Primary Completion: 2032-03-08
• Study Completion: 2042-03-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• thyroid cancer diagnosis

Exclusion Criteria

• patients unable to sign informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dynamic risk stratification	ten years from the primary treatment	impact of the different variables on the DRS
Overall survival	ten years from the primary treatment	impact of the different variables on the OS in patients treated with TKI for advanced thyroid cancer
Progression-free survival	ten years from the primary treatment	impact of the different variables on the PFS in patients treated with TKI for advanced thyroid cancer

Trial Locations

Locations (1)

Istituto Auxologico Italiano, IRCCS; 🇮🇹 Milan, Italy