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Clinical Trials/NCT06645925
NCT06645925
Recruiting
N/A

Novel Soft Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Implant Placement in Posterior Mandible: A 1-year Randomized Clinical Trial

Misr International University1 site in 1 country22 target enrollmentNovember 1, 2025

Overview

Phase
N/A
Intervention
One Step Protocol
Conditions
Free Gingival Graft
Sponsor
Misr International University
Enrollment
22
Locations
1
Primary Endpoint
Keratinized tissue width
Status
Recruiting
Last Updated
3 months ago

Overview

Brief Summary

Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues. Several studies reported that, minimum of 2 mm keratinized tissue width is required to achieve long-term longevity. Insufficient keratinized mucosa leads to biofilm accumulation, soft tissue inflammation, eventually peri-implant mucositis and peri-implantitis. Hence, the aim of the present trial is to evaluate KTW gain, linear and volumetric changes in buccal soft tissue along with hard tissue alterations following implant restoration at sites treated either with delayed implant placement & simultaneous FGG or the conventional FGG protocol prior to implant placement.

Registry
clinicaltrials.gov
Start Date
November 1, 2025
End Date
December 30, 2027
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Abo El Futtouh

CEO and Clinical Director

International Dental Contiuing Education

Eligibility Criteria

Inclusion Criteria

  • Adults at or above the age of
  • Lower Posterior missing tooth/ teeth with minimal KT \< 2mm
  • Sufficient alveolar ridge length minimum 13-15 mm to IAN
  • . Sufficient alveolar ridge width minimum of 6 mm
  • Patients able to tolerate surgical periodontal procedures.
  • Patients who provided an informed consent and accepted the one-year follow-up period.

Exclusion Criteria

  • Patients diagnosed with periodontal diseases (Caton et al., 2018).
  • Current or previous smokers.
  • Pregnant and lactating females.
  • Patients with medical conditions that would compromise the surgical procedures; uncontrolled diabetes mellitus, taking intravenous Bisphosphonates for treatment of osteoporosis.
  • Patients with active infection related to the site of implant.
  • Patients with parafunctional habits.
  • Patients with shallow vestibule

Arms & Interventions

One Step Protocol

FGG simultaneous with delayed implant placement

Intervention: One Step Protocol

Two Steps protocol

Conventional FGG protocol, prior to implant placement

Intervention: Two Steps Protocol

Outcomes

Primary Outcomes

Keratinized tissue width

Time Frame: 0 - 3 - 6 - 12 months

Measure Clinically and Digitally at 0 - 3 - 6 - 12 months postoperative

Secondary Outcomes

  • Midfacial margin changes(12 Months)
  • Crestal bone level changes(12 Months)
  • Bone labial to the implant(12 Months)
  • Survival Rate(12 Months)
  • Linear changes in buccal soft tissue contour(0-3, 0-6, 0-12 Months)
  • Interdental Papilla height changes(12 months)

Study Sites (1)

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