Effect of Grapefruit Juice and Exercise on Cortisol Levels
试验速览
- 阶段
- 不适用
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Plasma cortisol change from baseline at 45 minutes
研究概览
简要总结
The purpose of this study is to determine whether grapefruit juice alters the metabolism of cortisol following intense exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Young men and women, not taking medications known to alter glucocorticoid metabolism
排除标准
- •Diabetes, uncontrolled hypertension, obesity, any medication known to interact with grapefruit juice
研究组 & 干预措施
Grapefruit juice
12.5 OZ Grapefruit juice: Subject will ingest grapefruit juice 12.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon prior to their evening visit
干预措施: Grapefruit juice (Other)
Apple juice
10.5 OZ Apple juice: Subject will ingest apple juice 10.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon 3 hours prior to their evening visit.
干预措施: Apple juice (Other)
结局指标
主要结局
Plasma cortisol change from baseline at 45 minutes
时间窗: Baseline, 45 minutes
Plasma cortisol levels will be collected at baseline and 45 minutes post-exercise for the Grapefruit visit intervention and for the Apple juice intervention. The interventions are acute ( 1 day), there is no follow up. The interventions are at least 1 week apart. For a given subject, the estimated time for study completion for the 2 treatments is 14 to 30 days.
次要结局
- Change in plasma cortisol from 15 minutes to baseline(baseline, 15 minutes)