The Association Between Periodontal Disease and Malnutrition in a Group of Elderly People in Thailand.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Periodontal Diseases
- Sponsor
- Mahidol University
- Enrollment
- 78
- Locations
- 1
- Primary Endpoint
- Nutritional status
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
This study will be determine the association between periodontitis and malnutrition status in older adult.
Detailed Description
Ageing may accompany with an accumulation of diseases and impairments cause by physiological, socioeconomic and psychological changes. The older adults are more prone to nutritional deficiencies due to combination of factors such as ageing, excessive polypharmacy, general health decline, poor socioeconomic status, cognitive decline, poor appetite, impaired efficacy of swallowing and limit eating ability. Periodontitis is a multifactorial disease predominantly a bacterial infection involving the dental biofilm or dental plaque. Periodontitis increases in extent and severity across a large proportion of the human population with ageing. The effects of ageing on the immune system include distinct alterations in both innate and adaptive immune-cell function and effector biomolecules, resulting in processes reflecting immunosenescence, immunoactivation and inflammaging. Moreover, genetic contribution alters immunity and inflammation that play a role in the dysregulation of host responses in ageing. The combination of chronic antigenic burden and uncontrolled inflammatory response can enhance immunosenescence and ageing-associated disease. Periodontitis also has an effect on food intake, nutritional status and quality of life in older adults. However the relationship between chronic periodontitis and malnutrition in older adult is not clear and needs further study. In this study will be determine the association between periodontitis and malnutrition status in older adult.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects who has aged ≥ 60 years old.
- •Subjects who not receive periodontal treatment within the previous 6 months.
- •Subjects who are able to read Thai and express verbal communication.
- •Subjects who are functional independent older adults (get ≥ 12 points from Barthel Index for Activities of Daily Living) \[50, 51\].
- •Subjects who are cognitive functional independent older adults (get \> 23 points from Thai Mental State Examination) \[52\].
Exclusion Criteria
- •Subjects with completely edentulous area.
- •Subjects who require antibiotic prophylaxis for dental examination
Outcomes
Primary Outcomes
Nutritional status
Time Frame: 1 hour
The nutritional status of the participants will be measured by MNA (Mini Nutritional Assessment) questionnaire. The participants with scores ≥ 24 were classified as having a normal nutritional status, 17 to 23.5 were classified as at risk of malnutrition and \<17 were classified as malnutrition.
Periodontal status
Time Frame: 2 hour
The probing pocket depth and clinical attachment level were collected by clinical data collection. The participants who had 4 or more teeth with 1 or more sites with PPD ≥ 4 mm and with clinical attachment loss ≥ 3 mm at the same site was diagnosed as periodontitis.
Secondary Outcomes
- Variables that associated with malnutrition in older adult.(1 month)