TCTR20191205008终止不适用
Comparative study of the efficacy of intravitreal injection between Ziv-aflibercept and Bevacizumab for treatment of central retinal vein occlusion with macular edema
Invitation research fund Faculty of medicine, Khonkaen University0 个研究点目标入组 42 人开始时间: 2019年12月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 42
研究概览
简要总结
In this study, both IVZ and IVB showed significant visual improvement and CST reduction. When comparing the groups, ziv-aflibercept had insignificantly better visual and anatomical outcomes than bevacizumab in the treatment of ME secondary to CRVO. The mean number of injections was lower in the ziv-aflibercept group; however, the difference was not statistically significant. These results demonstrate the potential of ziv-aflibercept for the treatment of ME due to CRVO.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Diagnosis of CRVO with macular edema
- •- CST > 300 micron (by SD-OCT)
排除标准
- •1. one-eyed patient
- •2. external ocular infection ex. conjunctivitis , hordeolum and blepharitis
- •3. diabetic macular edema , age-related macular degeneration, epimacular membrane, vitreomacular traction and macular atrophy
- •4. History of laser within 6 mo
- •5. History of intraocular surgery within 6 mo (cataract sx, glaucoma sx)
- •6. History of intravitreal injection of steroid within 6 mo
- •7. History of intravitreal injection of anti-VEGF within 8 wk
- •8. Can't take fundus photo and OCT due to cataract, vitreous hemorrhage, corneal scar and pupillary constriction
- •9. U/D : myocardial infarction, stroke and uncontrolled HT
- •10. uncooperative patient ex. spine disease
- •11. pregnancy / planning of pregnancy within 12 mo
- •12. can't follow-up
研究者
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