Effects of Yoga on Bone Metabolism in Premenopausal Women

Not Applicable

Completed

• Conditions: Bone Health; Osteoporosis
• Interventions: Other: Yoga Group

• Registration Number: NCT02163668
• Lead Sponsor: University of Oklahoma

Brief Summary

This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years. The style of Yoga used was power Yoga that involved postures with a jumping component. The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Primary Completion: 2010-06
• Study Completion: 2012-04
• Status Verified: 2014-06
• Study First Submitted: 2014-06-09
• Study First Submitted QC: 2014-06-13
• Last Update Submitted: 2014-06-13
• Study First Posted: 2014-06-16
• Last Update Posted: 2014-06-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 47

Inclusion Criteria

• participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study
• did not have chronic back or joint problems or cardiovascular disease
• not taking antihypertensive drugs or any medication that affects bone density
• not taking hormonal contraception
• they self-reported having regular menstrual cycles.

Exclusion Criteria

• body weight more than 300 pounds

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Yoga group	Yoga Group	8 months of progressive Yoga training

Primary Outcome Measures

Name	Time	Method
Change in bone mineral density from baseline to 8 months	pre and post 8 months training
change in bone turnover markers	pre and post 8 month intervention
change in tibia bone characteristics	pre and post 8 month intervention	changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)
Changes in muscular strength	pre and post 9 month intervention	Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises
Change in arterial compliance	pre and post 8 month interventon	Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis.
Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3)	pre and post 8 month intervention

Secondary Outcome Measures

Name	Time	Method
Daily Calcium intake	pre and post 8 month intervention	Calcium intake is a potential confounding variable. Participants were encouraged to increase their calcium intakes if found to be low before the intervention began.
Menstrual History	pre and post 8 month intervention	This information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test.
Dietary intake	At baseline at the same time as other outcomes, about 2 weeks before the beginning of the yoga training	Three day dietary logs were recorded by participants before the exercise intervention. They were analyzed for caloric intake and nutrient composition using the Diet Analysis Plus 9 software.
Change in physical activity levels	pre and post 8 month intervention	Physical activity levels estimated by the bone-specific physical activity (PA) questionnaire to monitor their PA outside of the intervention
Change in body composition	pre and post 8 month intervention

Trial Locations

Locations (1)

Department of Health and Exercise Science, University of Oklahoma; 🇺🇸 Norman, Oklahoma, United States