Comparison of Effectiveness of Levetiracetam With Phenytoin in Postcraniotomy Seizure in the Patients with Supratentorial Brain Tumors :RCT-Single Blind
Phase 3
Recruiting
- Conditions
- Comparison of Effectiveness of Levetiracetam With Phenytoin in Postcraniotomy Seizure in the Patients with Supratentorial Brain Tumors.
- Registration Number
- IRCT20150419021837N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
The patients with age higher from 18years with Supratentorial Tumors need to Craniotomy&Liver & Renal function,Creatinine lower from1.5× upper limit of normal (ULN), Aspartate Aminotransferase lower from3× ULN, Alanine Aminotransferase lower from 3× ULN and Bilirubin lower from1.5× ULN)
Exclusion Criteria
History of Allergy to the Two Drugs,History of Seizere,Posterior Fossa Tumors,Pregnancy&History of Colostomy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Siezure. Timepoint: Days of 7,30&90 Post Craniotomy. Method of measurement: Observation by the nurse or physicion.
- Secondary Outcome Measures
Name Time Method Complications of Skin ,Renal&Liver. Timepoint: Days of 7,30&90 Post Craniotomy. Method of measurement: Observation of Skin &Liver&Renal lab data.