Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children

Phase 3

Recruiting

• Conditions: Helicobacter Pylori Infection
• Interventions: Drug: Nitazoxanide; Drug: Metronidazole; Drug: Clarithromycin; Drug: Proton pump inhibitor

• Registration Number: NCT04415983
• Lead Sponsor: Tanta University

Brief Summary

Study of Nitazoxanide (NTZ) based therapeutic regimens for Helicobacter pylori in children

Detailed Description

Study of Novel triple Nitazoxanide (NTZ) based new therapeutic regimens for Helicobacter pylori in children

Study Timeline

• Status Verified: 2020-06
• Study Start: 2020-06-01
• Study First Submitted: 2020-06-01
• Study First Submitted QC: 2020-06-01
• Last Update Submitted: 2020-06-01
• Study First Posted: 2020-06-04
• Last Update Posted: 2020-06-04
• Primary Completion: 2030-10-01
• Study Completion: 2030-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Positive helicobacter infection.

Exclusion Criteria

• Previous treatment for H. Pylori.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Nitazoxanide group	Proton pump inhibitor	Clarithromycin, Nitazoxanide and Proton pump inhibitor
Traditional group	Proton pump inhibitor	Clarithromycin, Metronidazole and Proton pump inhibitor
Nitazoxanide group	Nitazoxanide	Clarithromycin, Nitazoxanide and Proton pump inhibitor
Traditional group	Metronidazole	Clarithromycin, Metronidazole and Proton pump inhibitor
Nitazoxanide group	Clarithromycin	Clarithromycin, Nitazoxanide and Proton pump inhibitor
Traditional group	Clarithromycin	Clarithromycin, Metronidazole and Proton pump inhibitor

Primary Outcome Measures

Name	Time	Method
Number of patients with cured helicobacter infection	6 months	Total number of patients with eradicated helicobacter infection

Trial Locations

Locations (1)

Sherief Abd-Elsalam; 🇪🇬 Tanta, Egypt