ISRCTN28592111已完成未知
The effect of glycopyrronium bromide on hypersalivation in patients with Parkinson's disease: a randomised, cross-over, double blind, placebo-controlled trial
Hospital Medisch Spectrum Twente (The Netherlands)0 个研究点目标入组 23 人开始时间: 2007年2月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 23
研究概览
简要总结
2010 results in https://pubmed.ncbi.nlm.nih.gov/20385892/ (added 15/01/2021)
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients with Parkinson's disease
- •2. Aged more than or equal to 18 years
- •3. Hypersalivation score more than or equal to five (on a scale from one to nine)
- •4. Patient or family is able to score the extent of hypersalivation
排除标准
- •1. Hypersensitivity to glycopyrronium bromide, sorbic acid or saccharin sodium
- •2. Myasthenia gravis
- •3. Symptomatic tachycardia
- •4. Coronary insufficiency
- •5. Heart rhythm disorders
- •6. Glaucoma
- •7. Pylorus stenosis
- •8. Paralytic ileus
- •9. Prostate hypertrophy
- •10 Patients using potassium chloride tablets, oral digoxin or oral corticosteroids
- •11. Kidney function disorders
- •12. Pregnancy or lactation
研究者
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