CTRI/2023/10/058546
Not yet recruiting
Phase 2
Comparison of outcome in Terlipressin and ultra-low dose Terlipressin plus noradrenalin infusion in HRS-AKI patients of ACLF - NI
on sponsered0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Health Condition 1: K77- Liver disorders in diseases classified elsewhere
- Sponsor
- on sponsered
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •ACLF as per APASL criteria
- •AKI at admission as defined by ICA\-AKI criteria
- •HRS\-AKI grade II \& grade III as defined by ICA 12 hour of admission
Exclusion Criteria
- •Age \<18 years \>70 years
- •Septic shock
- •Patient with HCC outside Milan’s criteria
- •Severe Hyponatremia (Na \<120 MEq/L)
- •Patients with RH failure, CAD, PVD, arrhythmias and cardiomyopathy
- •Pregnancy or Lactating mother
- •Grade III/IV HE or Shock requiring inotropes or patients on mechanical ventilator at time of randomization
- •In\-hospital new AKI
- •Active urinary sediments – 2\+ albumin or above, dysmorphic RBCs
- •Known CKD, obstructive uropathy
Outcomes
Primary Outcomes
Not specified
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