Late Onset Postoperative Nausea and Vomiting

Not Applicable

Completed

• Conditions: Postoperative Nausea and Vomiting
• Interventions: Drug: Midazolam, dexamethasone; Drug: Ondansetron, Dexamethasone; Drug: Placebo

• Registration Number: NCT00918190
• Lead Sponsor: King Khaled Eye Specialist Hospital

Brief Summary

The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.

Detailed Description

The authors will study the effect of many antiemetics on the occurrence of nausea and vomiting following strabismus surgery in pediatrics.

Study Timeline

• Study Start: 2009-06
• Study First Submitted: 2009-06-10
• Study First Submitted QC: 2009-06-10
• Study First Posted: 2009-06-11
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-10
• Last Update Posted: 2021-10-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• children undergoing elective strabismus surgery under general anesthesia

Exclusion Criteria

• children experienced retching or vomiting
• children who have taken anti-emetic medications, antihistaminics, steroids, or psychoactive drugs within 24 hours before surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Midazolam, Dexa group	Midazolam, dexamethasone	use of midazolam and dexamethasone
Ondansetron-Dexa group	Ondansetron, Dexamethasone	Use 2 different antiemetics
Placebo	Placebo	Saline will be given

Primary Outcome Measures

Name	Time	Method
Efficacy of antiemetics combination	3 days

Trial Locations

Locations (1)

king Khaled Eye Specialist hospital; 🇸🇦 Riyadh, Saudi Arabia