The effect of vitamin D on people with prediabetes

Not Applicable

Completed

• Conditions: Prevention of the development of diabetes in people with prediabetes; Nutritional, Metabolic, Endocrine; Diabetes mellitus

• Registration Number: ISRCTN51643592
• Lead Sponsor: Aristotle University of Thessaloniki

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35167764/ (added 16/02/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36295786/ (added 14/02/2024)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-02-01
• Study Start: 2022-01-28
• Last Update Posted: 27 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1. Men and women with prediabetes aged 60 years and older
2. Listed on the registry of the Open Care Center for the Elderly of the Municipality of Eastern Thessaloniki, Greece.
3. Prediabetes diagnosed according to the criteria of the American Diabetes Association (ADA), either by impaired fasting plasma glucose (IFG) [fasting plasma glucose (FPG): 100–125 mg/dl] or impaired glucose tolerance (IGT) [2-h plasma glucose in 75 g oral glucose tolerance (OGTT): 140–199 mg/dl] or by values of glycated hemoglobin (HbA1c) between 5.7% (39 mmol/mol) and 6.4% (46 mmol/mol)

Exclusion Criteria

1. Pre-existing diabetes mellitus
2. Normal glucose levels
3. Any medical conditions that could potentially affect the outcomes of the study or increase the risk of complications following vitamin D supplementation (nephrolithiasis, hypercalcemia, hyperparathyroidism, sarcoidosis, and chronic renal disease [stages 3 to 5 / estimated glomerular filtration rate <45 ml/min/1.73m²])
4. Malignancies
5. Inflammatory or rheumatic diseases
6. Psychiatric conditions

Study & Design

• Study Type: Interventional
• Study Design: Not specified