NL-OMON42523尚未招募不适用
The role of perivascular adipose tissue in the regulation of insulin sensitivity through muscle microvascular recruitment in non-obese and obese individuals - PVAT, metabolism and vascular health
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Caucasian
- •- age 18-60 years
- •- BMI is *23 and <40 kg/m2
- •To obtain enough variation between individuals 30 individuals with a wide range of BMI will be recruited:
- •o 10 individuals with a BMI 23-28
- •o 10 individuals with a BMI 28-34
- •o 10 individuals with a BMI 34-40
排除标准
- •- Documented CVD
- •- Diabetes mellitus
- •- Stage 2 hypertension (resting blood pressure >160/100 mmHg)
- •- History of severe inflammatory conditions in the past 15 years
- •- Recent infections
- •- recent history (<12 months) of high alcohol use > 4 U/day, more than 3 days in a row
- •- Use of medication potentially affection insulin sensitivity, microvascular function or inflammation
- •- Use of anticoagulants (types Warfarin and Coumadin derivatives) that can increase the risk of bleeding during the muscle biopsy (exception is made for aspirin).
- •- Malignancies (except those of the skin), renal and hepatic diseases.
- •- Recent (<6 months) marked (>10%) changes in body weight.
研究者
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