RE-PAIR: the relation between parent-adolescent interactions and depressive symptoms in adolescents

Recruiting

Conditions: Depression
Major Depressive Disorder (MDD)
10027946
10016214

Registration Number: NL-OMON52729

Lead Sponsor: niversiteit Leiden

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 480

Inclusion Criteria

, Adolescents in depressive group:
• Aged between 11-17 years.
• Living with at least one primary caregiver
• At least one primary caregiver is willing to participate in the study
• Current depressive episode (having symptoms at least 2 months prior to the
diagnostic interview)
• Major depressive disorder as primary diagnosis, Adolescents in control group:
• Aged between 11-17 years.
• Living with at least one primary caregiver
• At least one primary caregiver is willing to participate in the study

Exclusion Criteria

Adolescents with major depressive disorder:
• Primary psychiatric disorder (Axis I), other than MDD.
• Comorbid eating disorders/mental retardation/psychoses/addictions (SUD)
• Use of antidepressants (i.e. SSRIs or TCAs), unless in a constant dosage.
• No good command of the Dutch language, Adolescents in the control group:
• Current psychiatric disorder
• History of psychiatric disorder in the past two years
• Lifetime depressive episode
• History of psychotherapy or other psychological treatment
• No good command of the Dutch language
• Use of medication for mental disorders or sleep medication, Additional fMRI
exclusion criteria:
• Metal implants, clips, stents, or pacemakers
• Braces
• Current pregnancy

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>We will study the quality of the parent-child interactions, primarily based on<br /><br>the influence of parental criticism and empathy and the adolescent's mood.<br /><br>We will also investigate the predictive value of the interactions on the course<br /><br>of the complaints of the adolescents, controlled for possible treatment.</p><br>

Secondary Outcome Measures