RPhotobiomodulation therapy as an adjunct therapy in burn wound care
Phase 1
- Conditions
- Health Condition 1: T212- Burn of second degree of trunkHealth Condition 2: T212- Burn of second degree of trunk
- Registration Number
- CTRI/2024/06/068433
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients having second degree superficial or deep dermal burns within 24 hours of injury, with 1.TBSA involved (1-5 %) in the upper or lower limbs, chest, abdomen and back.
2.Aged between 18 to 65 years
3. Hemodynamically stable
4. Not taking medication for any ailment
Exclusion Criteria
1.Presence of gangrene,
2.Pregnancy
3.Photosensitivity
4.Uncontrolled systemic disease
5.Chronic skin disease
6. Diagnosed uncontrolled mental illness, alcoholism or other addictions
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Time taken for epithelization/ appearance of granulation tissueTimepoint: 12 weeks
- Secondary Outcome Measures
Name Time Method 1.Pain : visual analog scale (VAS). <br/ ><br>2.Biomarkers in serum: IL-1ß, IL-6, TNF-a, Precalcitonin, CRP levels. (on 1st and last visit) <br/ ><br>3.Pain markers – Substance P /COX2 <br/ ><br>4.Quality of Scar <br/ ><br>Timepoint: 12 weeks