Extubation of Patients on ECLS is Associated With a Reduction in Complications Related to Mechanical Ventilation: Retrospective Single-centre Study

Completed

• Conditions: Extra-Corporeal Life Support

• Registration Number: NCT03295357
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

There are no clear recommendations concerning the management of patients on ECLS (Extra-Corporeal Life Support). Many teams keep patients sedated until removal of the ECLS so as to avoid accidents, notably decannulation. Moreover, there are few publications on the subject, all the more so as the extubation of patients on ECLS (Extra-Corporeal Life Support) is a recent practice. Nonetheless, it is becoming more and more frequent in the cardiovascular ICU of Dijon University Hospital. We therefore wished to evaluate the benefits of this practice by comparing 2 populations: those with extubation while on ECLS (Extra-Corporeal Life Support) and those without.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-05
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-09
• Study First Submitted: 2017-09-25
• Study First Submitted QC: 2017-09-25
• Last Update Submitted: 2017-09-25
• Study First Posted: 2017-09-27
• Last Update Posted: 2017-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients over 18 years who were placed on ECLS between 1/01/14 and 31/12/15

Exclusion Criteria

• Patients under 18 years old
• Patients on ECLS for a heart transplant
• Patients who died within the first 48 hours following the initiation of ECLS

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of VAP (ventilator-associated pneumonia) during hospitalisation in the ICU	At baseline

Trial Locations

Locations (1)

Chu Dijon Bourogne; 🇫🇷 Dijon, France