Local Anaesthesia for Hernia surgery

Completed

• Conditions: Unilateral inguinal hernia, without obstruction or gangrene,

• Registration Number: CTRI/2018/04/013131
• Lead Sponsor: Department of Anaesthesiology

Brief Summary

1.

Purpose:

I.              I.            To compare 0.5% bupivacaine with 0.5% ropivacaine, both in combination with 2% lignocaine-adrenaline regarding efficacy, safety and duration of post-operative analgesia in the patients undergoing unilateral inguinal hernia repair.

II.            To document complications, if any.

Results were as follows:

1.    The mean age of patients in our study was 48.6±15.56 years in Group LB and 46.48±14.03 years in Group LR.

2.    The mean weight (kg) of the patients in Group LB was 62.91±6.89 and in Group LR was 61.71±6.44.

3.    In Group LB, 25 (71.42%) patients belonged to ASA grade I, 10 (28.57%) belonged to ASA grade II and none to ASA grade III. While in Group LR, 27 (77.14%) patients were of ASA grade I, 8 (22.85%) were of ASA grade II and none in ASA grade III.

4.    In Group LB, 13 (37.14%) patients had hernia on the right side and 22 (62.85%) on the left side as compared to Group LR where 17 (48.57%) patients had hernia on the right side and 18 (51.42%) on the left side.

5.      In group LB, the onset was earlier (10.15±1.49 min) as compared to Group LR (11.4±1.71 min).

6.      Duration of surgery in Group LB was 59.34±10.90 min and in Group LR was 61.22±11.02 min.

7.      Preoperative VAS score was less in group LB (0.64±0.54) as compared to Group LR (0.77±0.49). VAS at the time of shifting was found to be more in Group LB (0.94±0.53) than in Group LR (0.91±0.50) patients.

8.      Seventeen (48.57%) patients in Group LR required infiltration of sac as compared to three (8.57%) in Group LB.

9.      Duration of analgesia was significantly longer in Group LR (481.71±70.52 min) as compared to Group LB (236.57±35.5 min).

10.  There was no statistically significant difference in haemodynamic parameters of HR, SBP, DBP and MAP of two groups at any given time.

11.  No complications related to the procedure or drugs were observed in our study.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10-09
• Study Completion: 2017-09-09
• Last Update Posted: 2019-01-24

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 70

Inclusion Criteria

1)ASA Grade I, II and III 2)scheduled for uncomplicated inguinal hernia repair.

Exclusion Criteria

1)Patient refusal 2)Patients with known hypersensitivity to local anaesthetics 3)Patients with ASA grade IV or more 4)Paediatric age group (<18 years) 5)Morbid obesity (BMI >35kg/m2) 6)Complicated hernias such as irreducible, strangulated, incarcerated or recurrent hernia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the efficacy of single-puncture technique of local anaesthesia for inguinal hernia repair.	1 year

Secondary Outcome Measures

Name	Time	Method
To compare 0.5% bupivacaine with 0.5% ropivacaine, both in combination with 2% lignocaine-adrenaline regarding efficacy, safety and duration of post-operative analgesia in the patients undergoing unilateral inguinal hernia repair.	1 year

Trial Locations

Locations (1)

RNT Medical College; 🇮🇳 Udaipur, RAJASTHAN, India

RNT Medical College

🇮🇳Udaipur, RAJASTHAN, India

Aditi Narang

Principal investigator

9587179929

draditinarang@gmail.com