Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study

Not Applicable

Completed

• Conditions: Overweight; Obesity
• Interventions: Dietary Supplement: Whey Protein; Dietary Supplement: Whey Protein and Resistance Exericse; Other: Whey Protein and RISE exercise routine

• Registration Number: NCT01960335
• Lead Sponsor: Skidmore College

Brief Summary

Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy. For example, increased whey protein ingestion with and without exercise training is associated with enhanced weight loss, body composition and subjective hunger in overweight and obese individuals. Our findings suggest that the effects of whey protein ingestion occur independent of a calorie-restricted diet and to a greater extent in individuals following a combined exercise program of resistance exercise, sprint intervals, stretching/yoga/pilates, and aerobic exercise training compared to standard resistance training.

Detailed Description

This study was a 16 week whey protein and exercise training intervention in middle aged overweight/obese adults. Subjects were randomized into 3 groups: Whey protein only consumed as 20 grams per serving three times per day (total 60 grams per day) (WP); Whey protein and resistance exercise training (WP-RT); and Whey protein and combined exercise training (P+RISE). All outcomes, including the primary outcome of visceral fat was measured at baseline (week 0) and post-intervention (week 17) in all study subjects.

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2012-01
• Study Completion: 2012-09
• Status Verified: 2013-10
• Study First Submitted: 2013-10-05
• Study First Submitted QC: 2013-10-09
• Last Update Submitted: 2013-10-09
• Study First Posted: 2013-10-10
• Last Update Posted: 2013-10-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

• healthy, overweight or obese, inactive

Exclusion Criteria

• smoker, exercise-trained, recent weight loss, heavy caffeine-consumer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Whey Protein Only	Whey Protein	Ingestion of whey protein only (20 grams per serving) consumed 3X/day along with ad libitum diet for a total of 60 grams per day. One serving was consumed within 1 hour of waking in the morning; a second serving was consumed mid-afternoon; and a third serving was consumed within 2 hours of going to sleep at night.
Whey Protein and RISE exercise routine	Whey Protein	Ingestion of whey protein (20 gram serving) 3X/day: one serving within an hour of waking in the morning; a second serving mid-afternoon or within 1 hour immediately following the RISE exercise bout; and a third serving within 2 hours of going to bed at night.
Whey Protein and Resistance Exericse	Whey Protein and Resistance Exericse	Ingestion of whey protein (20 grams per serving) 3X/day: one serving within an hour of waking in morning; a second serving mid-afternoon or within 1 hour immediately following a resistance exercise bout on exercise days; and a third serving within 2 hours of going to bed at night.
Whey Protein and Resistance Exericse	Whey Protein	Ingestion of whey protein (20 grams per serving) 3X/day: one serving within an hour of waking in morning; a second serving mid-afternoon or within 1 hour immediately following a resistance exercise bout on exercise days; and a third serving within 2 hours of going to bed at night.
Whey Protein and RISE exercise routine	Whey Protein and RISE exercise routine	Ingestion of whey protein (20 gram serving) 3X/day: one serving within an hour of waking in the morning; a second serving mid-afternoon or within 1 hour immediately following the RISE exercise bout; and a third serving within 2 hours of going to bed at night.

Primary Outcome Measures

Name	Time	Method
change in visceral fat	baseline and 17 weeks

Trial Locations

Locations (1)

Health & Exercise Sciences Department, Human Nutrition and Metabolism Laboratory, Skidmore College; 🇺🇸 Saratoga Springs, New York, United States