The effect of Systemic Administration of Cholecalciferol on the Rate of Orthodontic Tooth Movement of Maxillary Canines among subjects with Vitamin D deficiency- A Randomized Control Clinical Trial
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Rate of tooth movement (Maxillary Canine distal movement)
研究概览
简要总结
The effect of vitamin D supplements on rate of tooth movement (canine retraction) has not been evaluated in humans in previous studies. Hence this randomized clinical controlled trial is proposed to evaluate the effect of vitamin D supplementation in vitamin D deficient subjects on amount of orthodontic tooth movement during canine retraction phase of fixed orthodontic therapy.
Null hypothesis states that there is no effect of cholecalciferol on the rate of orthodontic tooth movement during canine retraction phase among subjects with vitamin D deficiency.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 12.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients planned to be treated with fixed orthodontic treatment following maxillary first premolars extraction
- •Patients with Class I, Class II and Class III malocclusion
- •Deficient serum Vitamin D level (5-29.9 ng/ml)
- •Patients with full set of permanent teeth in maxillary arch
- •Age Group: 12-25 years.
排除标准
- •Patients with severely deficient vitamin D level (≤5 ng/ml)
- •Patients with any malocclusion treated with non-extraction or extraction of teeth other than first premolars in maxillary arch
- •Patients with Cranio-facial syndromes and Cleft lip and palate
- •Patients with severe crowding or blocked out maxillary canines.
- •Patients already on Vitamin D supplements
- •Patients with liver, kidney, thyroid and parathyroid disorders.
- •Orthodontic retreatment cases.
结局指标
主要结局
Rate of tooth movement (Maxillary Canine distal movement)
时间窗: T0- At start of canine retraction | T1- Three months after start of canine retraction
次要结局
- Mesial movement of molar(T0- At start of canine retraction)
研究者
Dr Akhilesh Singhal
Post Graduate Institute of Medical Education and Research, Chandigarh