JPRN-UMIN000014299
Completed
Phase 2
Phase II study of erlotinib monotherapy for patients with advanced stage of non-small cell lung cancer, undetectable epidermal growth factor receptor (EGFR) mutations by PNA LNA PCR clamp method, but positive immuno-staining with anti-EGFR mutation-specific antibodies. - OPH-RM/P-LC-1401
Dept. of Respiratory Medicine, Osaka Police Hospital0 sites7 target enrollmentJuly 1, 2014
Conditionson-small cell lung cancer
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- on-small cell lung cancer
- Sponsor
- Dept. of Respiratory Medicine, Osaka Police Hospital
- Enrollment
- 7
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\. Problematic infection that requires anti\-biotic, anti\-fungal agent or anti\-viral agent. 2\. Current or previous history of pulmonary fibrosis, interstitial pneumonitis or drug\-induced pneumonia, revealed by chest CT or with clinical symptoms. 3\. A history of severe hypersensitivity against erlotinib 4\. Difficulty in oral administration of erlotinib, functional / organic impairment or inflammatory bowel disease that disturbs absorption of erlotinib 5\. Another active advanced malignancy that requires any concurrent treatment with treatment for lung cancer. 6\. Pregnant or lactation women, or women with known or suspected pregnancy and men who want let to pregnancy 7\. Psychologically ineligible 8\. Decision of ineligibility by a physician.
Outcomes
Primary Outcomes
Not specified
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