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RNA Sequencing of Individual Versus Wastewater - SARS-CoV2

Completed
Conditions
Infection Viral
Interventions
Other: NO INTERVENTION
Registration Number
NCT05041764
Lead Sponsor
Centre Hospitalier Universitaire de Nice
Brief Summary

The aim is to compare the percentage of the different SARS-CoV2 lineages that are detected in wastewater samples with matched clinical samples. About 1,400 swab samples from patients living in Nice were tested by Biogroup between Oct 19th and Oct 23rd (Week 43 of 2020). The sequence of 81 PCR positive samples, corresponding to all samples that were unambiguously assigned to one of the wastewater catchment areas and their lineage was determined. These values were compared to values measured in wastewater.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1409
Inclusion Criteria
  • whole population tested in Nice during W43 of 2020
Exclusion Criteria
  • none

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
PCR negativeNO INTERVENTIONsamples that are p negative for the detection of SARS-CoV2. T
PCR positiveNO INTERVENTIONsamples that are positive for the detection of SARS-CoV2. The SARS-CoV2 sequence of positive samples is provided, together with an indication about patient's neigborhood, corresponding to one of the 21 different spots which wastewater was analyzed
Primary Outcome Measures
NameTimeMethod
RTqPCR result1 month

positive ou negative result to SAR-Cov2

SARS-CoV2 sequence1 month

analyse of SARS-CoV2 sequence (in the case of positive samples)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Ipmc . Cnrs

🇫🇷

Sophia Antipolis, France

Nice Hospital

🇫🇷

Nice, France

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