Impact of Spirulina Corn Soy Blend on Protein Energy Malnourished and Iron Deficient children aged 6-23 months in Ndhiwa Sub-County-Kenya

Not Applicable

• Conditions: Nutritional, Metabolic, Endocrine

• Registration Number: PACTR202004842786087
• Lead Sponsor: Dorothy Othoo

Brief Summary

Children in SCSB significantly recovered from PEM by their RBP status (RR=3.07;CI 2.62-2.71;p=0.004), their WHZ-score, (at month 3(RR=2.21;CI:0.09-0.357;p=0.007), month4 (RR=2.49;CI:0.09-1.20;p=0.002), month 5 (RR=2.73;CI:0.00-0.47;p<0.001) and month 6(RR=3.1;CI:0.00-0.48; p<0.001) and by their WAZ-scores at month 3(RR=1.96;CI:0.15-0.38;p=0.002), month 4 (RR=2.17;CI:0.04-0.38;p<0.001), month 5(RR=2.36;CI:0.00-0.46;p<0.001) and month 6(RR=3.58;CI 2.91-3.88;p<=0.001). Magnitude of change in RBP status of children in EG1 was significantly higher (d=0.862;p=0.001) than those who consumed CSB and placebo. Children in SCSB had higher recovery rates (Log-rank-X2; p<0.001) than those in CSB and placebo. Children in SCSB were 3 times more likely to have normal RBP status, WHZ and WAZ than those who consumed CSB and those in placebo.

Detailed Description

Not available

Study Timeline

• Results First Posted: 2016-12-05
• Study Start: 2020-04-17
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 276

Inclusion Criteria

MUAC 115mm to 125mm
WHZ score >-3 to <-2
WAZ score >-3 to <-2

Exclusion Criteria

Severe acute malnutrition HAZ <-3 Zscores
Bilateral edema
Pre-exsisting conditions such as cancers, heart, kidney and liver conditions
on intervention by the time of recruitment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retinol Binding Protein;Hematocrit ;WHZ;WAZ

Secondary Outcome Measures

Name	Time	Method
Dietary intake;Morbidity