Comparing Injection Palonosetron alone and Palonosetron with Dexamethasone for preventing vomiting in post operation period in cholecystectomy patients
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/11/059627
- Lead Sponsor
- Dr SHIVAKUMAR G
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.PATIENTS BETWEEN AGE GROUP 18 YEARS TO 60 YEARS
2.PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY SURGERIES UNDER GENERAL ANAESTHESIA
3.PATIENTS BELONGING TO AMERICAN SOCIETY OF ANAESHESIOLOGISTS PHYSICAL STATUS GRADE I AND II
4.PATIENTS WILLING TO GIVE INFORMED CONSENT TO PARTICIPATE IN THE STUDY
Exclusion Criteria
1.RECEIVED ANTI EMETIC DRUGS OR DRUGS WITH ANTI EMETIC PROPERTY 24 HOURS BEFORE ANAESTHESIA
2.PATIENTS WITH HISTORY OF MOTION SICKNESS
3.PATIENTS WITH BODY MASS INDEX MORE THAN 30
4.PATIENTS WITH HISTORY OF GASTRO OESOPHAGEAL DISEASE
5.PATIENTS WHO ARE PREGNANT
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of Intravenous Palonosetron versus Palonosetron with dexamethasone on the incidence of early & delayed postoperative nausea & vomiting during first 24hrs after induction of general anaesthesia in laparoscopic cholecystectomy surgeriesTimepoint: 1 hour , 2 hours, 3hours , 6 hours,24 hours
- Secondary Outcome Measures
Name Time Method 1.To compare the severity of nausea & retching, need for rescue medications and to assess patient’s satisfaction. <br/ ><br>2.To compare the incidence of any adverse effects between the two drugs <br/ ><br>Timepoint: 1 hour , 2 hours, 3hours , 6 hours,24 hours