Oldest-old Patients Anesthesia in Orthopedic Surgeries

Completed

• Conditions: Anesthesia
• Interventions: Other: Patient' ages

• Registration Number: NCT06522178
• Lead Sponsor: Istanbul Medeniyet University

Brief Summary

Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades. As life expectancy increased, the rate of emergency and elective surgical interventions has also increased in the older age group. Although good health is required to reach an advanced age, over time, organ functions may deteriorate, and some challenges may develop that will negatively affect the balance of homeostasis. Stress, such as trauma or surgery, can cause deterioration in organ functions or aggravation of impaired functions. The risk of developing undesirable events is higher, due to the diminished reserve and function, during anesthesia applied to these patients. There is a limited number of studies in the literature about the relation between the anesthesia technique and morbidity and mortality in oldest old patients operated for orthopedic surgery. In this study, we aimed to analyze the data of the oldest-old patients operated on for orthopedic surgery between 2016-2022, retrospectively, and to investigate the relationship between anesthesia technique and adverse effects including morbidity and mortality.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-03
• Primary Completion: 2022-12-31
• Study Completion: 2024-01-01
• Status Verified: 2024-07
• Study First Submitted: 2024-07-22
• Study First Submitted QC: 2024-07-22
• Last Update Submitted: 2024-07-22
• Study First Posted: 2024-07-26
• Last Update Posted: 2024-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1356

Inclusion Criteria

• Aged 80 years and above
• Underwent orthopedic surgery

Exclusion Criteria

• Those who had the operation with local anesthesia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	Patient' ages	Group I patients contained those who were between 80 (included) and 89 (included) years of age.
Group 2	Patient' ages	Those who were 90 years of age and above were included in Group II

Primary Outcome Measures

Name	Time	Method
Mortality	one month after operation	postoperative mortality
Anesthesia Techniques	up to 6 hours	Data were also analyzed and compared with groups and between groups according to the applied anesthesia technique (general anesthesia versus regional anesthesia).
Type of operation	up to 6 hours	Orthopedic surgery type

Secondary Outcome Measures

Name	Time	Method
Presence and type of comorbidities	6 month period before operation	Hypertension, dementia, asthma, COPD (Chronic obstructive pulmonary disease), CHF (Chronic Heart Failure), CAD (Coronary artery disease), DM (Diabetes mellitus), valvular heart disease, history of pulmonary emboli, electrolyte imbalance, presence of cancer, renal diseases, history of cerebrovascular disease, endocrine diseases, neurologic diseases, other chronic diseases

Trial Locations

Locations (1)

Istanbul Medeniyet University; 🇹🇷 İ̇stanbul, Turkey