Study to Assess the Effects of High Protein Diet in Obesity, the LOWER Study
Not Applicable
Completed
- Conditions
- Obesity
- Interventions
- Dietary Supplement: High protein energy-restrictedDietary Supplement: Normal protein energy-restricted
- Registration Number
- NCT00862953
- Lead Sponsor
- University Medical Center Groningen
- Brief Summary
This program is carried out in a dedicated outpatient-clinic in the city of Hengelo for the evaluation and treatment of subjects with obesity. The program puts emphasis on intervention with appropriate diet and physical exercise, and supports the patients in achieving long-term behaviour changes. Interventions which are compared are normal vs high protein/low carb diets.
- Detailed Description
Assessment focuses on the effect of the specific diets on weight reduction after 3 months, and weight maintenance after 12 months.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 317
Inclusion Criteria
- Obesity with BMI > 27 kg/m2
Exclusion Criteria
- Recent loss of body weight (>10%)
- Underlying malignancy, HIV infection, psychiatric disease
- Pregnancy or breast feeding
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description High protein low carbohydrate High protein energy-restricted High protein low carbohydrate nutrition High protein normal carbohydrates High protein energy-restricted High protein normal carbohydrates Normal protein normal carbohydrate Normal protein energy-restricted Normal protein normal carbohydrate calory restricted nutrition Normal protein low carbohydrates Normal protein energy-restricted Normal protein low carbohydrate energy-restricted diet
- Primary Outcome Measures
Name Time Method Body weight 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hospital Hengelo
🇳🇱Hengelo, Netherlands