Assessment of the Efficacy of Hemodialysis on Uric Acid Clearance at End Stage Kidney Disease in Sohag University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- study of serum uric acid level in hemodialysis patients
研究概览
简要总结
Background: Uricemia dramatically rises with the stage of chronic kidney disease (CKD) and correlates with its mortality. Hemodialysis (HD) being the most used treatment at the end stage kidney disease in Sohag governorate , we sought to evaluate its efficacy on the clearance of uric acid (UAc) when used alone and twice per week.
Methods: A cross-sectional study of all consenting patients with CKD stage 5 recruited at random during hemodialysis sessions at hemodialysis unit in Sohag university hospital from July to December 2025. We collected socio-demographic data, relevant clinical information, hemodialysis related variables, and measured serum uric acid (SUA) levels before and after the dialysis to assess the uric acid clearance. A clearance between 65 and 80% and above 80% was considered as low and good efficacy of hemodialysis respectively
详细描述
Aim of the the work The aim of this study is to estimate the efficacy of Hemodialysis alone for uric acid clearance in patients on hemodialysis. In order to evaluate the need of adjuvant uric acid lowering therapy
Patients And Methods
- Type of The study:
Prospective cross-sectional study. 2. Place of the study:
Sohag University Hospital, department of Internal Medicine and hemodialysis unit. 3. Ethical aspect:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •We included all consenting adults aged 18 or older, on maintenance hemodialysis for at least 3 consecutive months receiving 2 to 3 sessions weekly
排除标准
- •Patients aged < 18 years old .
- •Patients on recent hemodialysis less than 3 months.
- •We excluded patients who were on Uric acid lowering therapy (UALT).
- •Patients received less than 4 hours of hemodialysis and those who had emergency dialysis.
结局指标
主要结局
study of serum uric acid level in hemodialysis patients
时间窗: during hemodialysis session 2 to 3 hours
milligrams per deciliter (mg/dL)
次要结局
未报告次要终点
研究者
Reham Hussien Abotaleb
Internal medicine resident doctor
Sohag University