Comparison of Adenoma Detection Rate Using Narrow Band Imaging Versus HD White Light Colonoscopy in Screening and Surveillance Colonoscopies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Adenoma detection rate
研究概览
简要总结
The aim of this study is to compare ADR using HD-NBI or HD-WLE during screening and surveillance colonoscopies.
详细描述
Background:
Despite recent advances in endoscopic technology adenoma miss rate still is up to 20% and contributes to the occurrence of interval cancers. Therefore, improved imaging modalities have been introduced to increase adenoma detection rate (ADR) during screening and surveillance colonoscopies. Recently, narrow band imaging (NBI; Exera II series, Olympus Corporation) was not significantly better than high definition white light colonoscopy (WLC) for the detection of patients with colorectal polyps, or colorectal adenomas1. However, Olympus' current Exera III series is characterized by better illumination of the bowel lumen and may be associated with a higher ADR than high definition WLC.
Methods:
Investigators performed a prospective evaluation in patients referred to the Department of Interdisciplinary Endoscopy at Jena University Hospital for screening or surveillance colonoscopy between January and November 2015 in daily clinical practice. Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal of the colonoscope (Exera III series, Olympus Corporation).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Screening colonoscopies
排除标准
- •Insufficient bowel cleansing
- •Age under 55years
研究组 & 干预措施
HD white light
Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal
干预措施: HD white light or NBI (Device)
HD narrow band imaging
Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal
干预措施: HD white light or NBI (Device)
结局指标
主要结局
Adenoma detection rate
时间窗: up to 60min
Adenoma detection rate
次要结局
未报告次要终点
研究者
Martin Bürger
Narrow band imaging does not increase adenoma detection rate compared to high definition white light colonoscopy in screening and surveillance colonoscopies
Jena University Hospital
