An Exploratory Study on the Impact of Prolonged Postoperative Endotracheal Extubation Time on Postoperative Complications in Gastric Cancer Patients With Severe Obstructive Sleep Apnea
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Postoperative complications
研究概览
简要总结
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
详细描述
This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients preoperatively diagnosed with resectable gastric cancer
- •Patients without distant organ metastasis
- •Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) >30 events/hour and SaO₂ <80%
- •Patients with cardiopulmonary function deemed suitable for surgery
- •Patients aged 18-85 years
- •Patients who voluntarily joined this study and provided written informed consent
排除标准
- •Patients with a history of or concurrent other malignant tumors
- •Patients who underwent palliative resection
- •Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
- •Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
- •Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study
结局指标
主要结局
Postoperative complications
时间窗: 48-72 hour
The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
次要结局
未报告次要终点