NL-OMON44132
Completed
Phase 2
A Phase I/II study to determine the safety and efficacy of a combination of anti-CD3 & anti-CD7 ricin A immunotoxins (T-Guard) for treating steroid-resistant acute graft-versus-host disease. - T-Guard for aGVHD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Xenikos BV
- Enrollment
- 10
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients suffering from severe acute GVHD (Grade II\-IV) that is progressing after 3 days, or nonimproving after 7 days, of prednisolone at 2 mg/kg a day.
Exclusion Criteria
- •Patients receiving concomitant investigational therapeutics for acute GVHD, including agents used
- •for GVHD prophylaxis, at the time of enrollment.
Outcomes
Primary Outcomes
Not specified
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