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Clinical Study of Guiyuan Decoction in Treating Decreased Ovarian Reserve Functio

Phase 1
Recruiting
Conditions
decline in ovarian reserve, DOR
Registration Number
ITMCTR2000004004
Lead Sponsor
onghua Hospital, Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

(1) The age ranged from 18 to 40 years (inclusive);
(2) Rare or frequent menstruation or menopause for at least 4 months;
(3) Serum FSH level at least twice: 10 U / L < FSH < 25 U / L (interval > 4 weeks);
(4) AFC < 5 or serum AMH level: 0.5ng/ml < AMH < 1.1ng/ml.

Exclusion Criteria

(1) Patients are undergoing radiotherapy and chemotherapy due to malignant tumor;
(2) Patients with Bilateral ovaries or uterus were removed due to gynecological surgery;
(3) Patients with Ovarian hypersensitivity syndrome and other endogenous FSH increasing patients;
(4) Patients with genital malformation;
(5) Patients with Severe cardiovascular and cerebrovascular diseases or liver and kidney dysfunction;
(6) Patients with mental disorders;
(7) Those who have used hormone drugs and other immune preparations in the past 3 months.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
TCM Syndrome Scale;Antimullerian hormone;Serum sex hormones;Uterus and ovarian ultrasound;
Secondary Outcome Measures
NameTimeMethod
Blood routine;sas;
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