Introduction of a Massive Transfusion Protocol - Evaluation Over Three Years
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 243
- 主要终点
- Coagulation in ROTEM
研究概览
简要总结
In 2008 at the University Hospital Zurich (USZ) a massive transfusion protocol was introduced. Based on laboratory diagnostics and point of care (POC) devices including ROTEM.
Goal of this retrospective study is to evaluate the influence of this algorithm on coagulation, use of blood products, coagulation factors and ROTEM evolution.
详细描述
In 2008 at the USZ a massive transfusion protocol was introduced. Based on laboratory diagnostics and POC (point of care) devices including ROTEM.
Goal of this retrospective study is to evaluate the influence of this algorithm on coagulation, use of blood products, coagulation factors and ROTEM evolution over three years (2008-2010)
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Massive transfusion
排除标准
- 未提供
结局指标
主要结局
Coagulation in ROTEM
时间窗: 3 years
Point of care devices are used in bleeding patients. In the university hospital of Zurich an algorithm in the case of massive bleeding was introduced in 2008. The primary outcome measure is to investigate the changes of ROTEM parameters in the sense of amelioration reflected by better coagulation by using goal directed transfusions.
次要结局
- Transfusion needs(3 years)
研究者
Oliver Theusinger
PD Dr med
University of Zurich