Effects of exercise training on depressive symptom and cognitive function in hemodialysis patients

Not Applicable

• Conditions: hemodialysis patients

• Registration Number: JPRN-UMIN000029372
• Lead Sponsor: The Department of Psychiatry, Kawagoe Clinic, Saitama Medical University

Brief Summary

In depression, cognitive function, and the NPI-Q, there were no significant effects. In subjective insomnia, a short-term effect in the intervention group compared to the control group was found. However, the effect had disappeared by the 12-month follow-up. In exercise self-efficacy, short- and long-term effects were found. A significant short-term effect in the resistance exercise. However, the effect was weakened in the long term.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-10-02
• Study Completion: 2019-01-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients who are contraindicated for exercise training. Concrete criteria are as follows: -Patients who were diagnosed with heart failure and whose subjective symptoms of heart failure worsened within the past week -Patients with unstable angina pectoris Myocardial ischemic patients with low threshold -Patients who developed acute myocardial infarction within the past month -Patients with severe left ventricular efflux stenosis (obstructive hypertrophic cardiomyopathy, etc.) -Patients with untreated exercise-induced severe arrhythmia (ventricular fibrillation, sustained ventricular tachycardia) -Patients with poorly controlled arrhythmia -Patients with active myocarditis / pericarditis -Patients with acute aortic dissection -Patients with other disorders in which exercise therapy is contraindicated (moderate or higher degrees of aortic aneurysm, severe hypertension, thrombophlebitis, embolism within the past 2 weeks, severe multiple organ disorder, etc.)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
depressive symptom: PHQ-9 cognitive function: MoCA-J pre-intervention, 3 months, 6 months, 12 months

Secondary Outcome Measures

Name	Time	Method
sleep quality: Athens insomnia scale behavioral and psychological symptoms of dementia: NPI-Q(The Neuropsychiatric Inventory Questionnaire) ADL: Barthel Index Physical function: Knee Extension Muscle Strength, Weight Bearing Index, Grip Strength pre-intervention, 3 months, 6 months, 12 months