Topical and Oral Regimen for Skin Health
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 74
- 试验地点
- 2
- 主要终点
- Changes in appearance of facial redness
研究概览
简要总结
The overall objective of this study is to assess how oral supplementation with Inner Calm and the use of topical Super Calm can affect the appearance of skin and inner wellness, such as redness, skin sensitivity, and reactionary skin.
详细描述
The landscape for skin health has expanded past a focused use of topicals to incorporate the use of supplementation. Notable examples include the ingestion of carotenoids and beta-carotene to augment skin antioxidant status or the role of diet on different skin conditions. The role of this investigation is to define how Inner Calm (oral supplementation) may promote healthier skin and how this may work in synergy with Super Calm (topical supplementation).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women aged 18-55
- •Fitzpatrick skin type 1-4
- •Self-perception as sensitive skin
排除标准
- •Exclusion Criteria:
- •Adults unable to consent
- •Individuals who are not yet adults (infants, children, teenagers)
- •Pregnant or breast-feeding women
- •Prisoners
- •Those who have used isotretinoin in the last 6 months
- •Those who have used products containing salicylic acid, beta hydroxyl acids or vitamins A, C, or E or topical retinoids or topical depigmenting agents (such as hydroquinone, kojic acid, azelaic acid, or others in opinion of the investigator) in the last 14 days
- •Those who are currently smoking or have smoked within the past 3 years.
- •Those who have had a recent surgical or cosmetic procedure in the last 3 months that can affect facial wrinkles, redness, or hyperpigmentation, such as botulinum toxin injections, chemical peels, laser-based therapies to the face, or face lift surgeries
- •Subjects with known allergy to any of the components of Inner Calm or Skin Calm
- •Those that are unwilling to discontinue use of any other nutritional supplements including antioxidants, herbs, or protein-based supplements for 2 weeks prior to and during their participation.
- •Subjects with a diagnosis of acne
结局指标
主要结局
Changes in appearance of facial redness
时间窗: 8 weeks
Photographic image analysis
Changes in appearance of facial pigmentation
时间窗: 8 weeks
Photographic image analysis
次要结局
- Subjective report of calmness of skin(8 weeks)
- Changes in appearance of facial redness(4 weeks)
- Subjective report of mood and energy(8 weeks)
- Changes in appearance of facial pigmentation(4 weeks)
- Changes in appearance of facial redness before and after treatment(8 weeks)
- Subjective report of skin reactivity(8 weeks)
- Subjective report of sleep quality and quantity(8 weeks)
- Subjective report of calmness of mind(8 weeks)