Role of Subsequent Atrial Tachycardia in Mechanisms of Persistent AF

Completed

• Conditions: Atrial Fibrillation
• Interventions: Procedure: Catheter ablation of subsequent atrial tachycardia

• Registration Number: NCT01896570
• Lead Sponsor: Johannes Gutenberg University Mainz

Brief Summary

In this study, the investigators aim to examine the prognostic role of subsequent Atrial Tachycardias (ATs) in the mechanisms of atrial fibrillation (AF). Therefore, the investigators compare patients who were randomly assigned to either undergo cardioversion after AF has been terminated to AT or further ablation until the achievement of sinus rhythm.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06
• Primary Completion: 2013-03
• Status Verified: 2013-07
• Study First Submitted: 2013-07-06
• Study First Submitted QC: 2013-07-10
• Last Update Submitted: 2013-07-10
• Study First Posted: 2013-07-11
• Last Update Posted: 2013-07-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• persistent AF for at least 1 months,
• age > 18 years,
• refractory to drug therapy,
• no prior ablation

Exclusion Criteria

• prior AF ablation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group B: ablation to SR	Catheter ablation of subsequent atrial tachycardia	After AT has been achieved, all subsequent AT were ablated with the endpoint of procedural SR termination

Primary Outcome Measures

Name	Time	Method
Arrhythmia-free survival	24 months after enrolment

Secondary Outcome Measures

Name	Time	Method
Type of Arrhythmia recurrence	24 months after enrolement

Trial Locations

Locations (1)

University Hospital Eppendorf, Dept. of Electrophysiology; 🇩🇪 Hamburg, Germany