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Clinical Trials/NCT07400640
NCT07400640
Recruiting
Not Applicable

Which Is More Effective in the Treatment of Postherpetic Neuralgia: Erector Spinae Plane Block or Transcutaneous Radiofrequency?

Diskapi Teaching and Research Hospital1 site in 1 country50 target enrollmentStarted: June 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
50
Locations
1
Primary Endpoint
VAS

Overview

Brief Summary

This observational study aims to compare the effectiveness of ultrasound-guided erector spinae plane (ESP) block and transcutaneous radiofrequency (RF) treatment in patients with postherpetic neuralgia. Pain intensity and neuropathic pain characteristics will be evaluated using the Visual Analog Scale (VAS) and the Self-Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) score.

Detailed Description

Postherpetic neuralgia is a challenging neuropathic pain condition that significantly affects quality of life. In routine clinical practice, patients are treated with either ultrasound-guided erector spinae plane block or transcutaneous radiofrequency therapy based on clinician preference and experience.

This observational study includes patients who have already completed one of these treatments as part of standard care in the Algology Clinic. No randomization or modification of treatment plans was performed for research purposes. Patients will be divided into two cohorts according to the treatment they received. Treatment outcomes will be retrospectively evaluated and compared using VAS and S-LANSS scores before treatment, immediately after treatment, and at 1-month follow-up.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Diagnosis of postherpetic neuralgia involving cervical, thoracic, or lumbar regions
  • Age between 18 and 80 years
  • Persistent pain despite conservative treatment
  • Baseline VAS score \> 5

Exclusion Criteria

  • Ophthalmic or extremity postherpetic neuralgia
  • Allergy to local anesthetics
  • Coagulopathy or use of antiplatelet therapy
  • Cognitive impairment preventing informed consent

Arms & Interventions

Erector Spinae Plane Block

Patients with postherpetic neuralgia who received ultrasound-guided erector spinae plane block as part of routine clinical care.

Intervention: Erector Spinae Plane Block (Procedure)

Transcutaneous Radiofrequency

Patients with postherpetic neuralgia who received transcutaneous radiofrequency treatment applied adjacent to the lesion area as part of routine clinical care

Intervention: Erector Spinae Plane Block (Procedure)

Outcomes

Primary Outcomes

VAS

Time Frame: Baseline, post-procedure 1 month

Pain intensity assessed by Visual Analog Scale (VAS): is a simple tool used in clinical trials to measure pain intensity. Patients rate their pain on a scale, typically from 0 (no pain) to 10 (worst imaginable pain). It provides a quick, quantitative assessment of subjective pain and is commonly used to evaluate treatment effectiveness before and after intervention.

Secondary Outcomes

  • S-LANSS(Baseline, post-procedure 1 month)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Damla Yürük

Supervisor Investigator

Diskapi Teaching and Research Hospital

Study Sites (1)

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