KCT0005744尚未招募未知
Observations of gut microbiome changes and clinical treatments of Korean medicine in Parkinson’s disease patients with constipation: an observational single-center pilot study
Kyung Hee University Oriental Medical Center0 个研究点目标入组 20 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational Study
入排标准
- 年龄范围
- 19(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •1. Age = 19 years
- •2. Patients diagnosed with Parkinson's disease according to the UK Brain Bank Criteria and whose onset age is 50 years or older
- •3. Patients who have no problem with cognitive function and communication, and who voluntarily agreed to participate in the present study through written consent
- •4. Patients who are diagnosed with functional constipation according to ROME III functional constipation diagnostic criteria
排除标准
- •1. If there is an active gastrointestinal disease (e.g., celiac disease, pernicious anemia, autoimmune gastritis, symptomatic diverticulosis, inflammatory bowel disease, irritable bowel syndrome, strictures, adhesions, varicosis or diverticulum of the esophagus, Meckel's diverticulum, etc. ). However, participation is permitted for chronic gastritis
- •2. Patients with a history of serious heart disease such as myocardial infarction or severe heart failure (New York Heart Association classification (NYHA) Class III or higher)
- •3. Patients diagnosed or treated for cancer within 6 months
- •4. Patients with a history of chronic alcohol or substance abuse
- •5. Patients diagnosed with dementia or whose MMSE < 24
- •6. Patients with mental illness (eg, autism spectrum, schizophrenia, etc.)
- •7. Patients with unstable vital signs (eg, systolic blood pressure greater than 160mmHg even while taking hypertension medication)
- •8. Patients diagnosed with HIV
- •9. Patients with a family history of Parkinson's disease
- •10. Patients with atypical or secondary Parkinson's syndrome
- •11. Patients diagnosed with degenerative brain diseases other than Parkinson's disease (eg Alzheimer's type dementia)
- •12. Patients with other brain diseases (eg, brain tumor, traumatic brain injury, etc.)
- •13. Patients diagnosed with other cerebrovascular abnormalities (cerebral hemorrhage, subarachnoid hemorrhage, cerebral aneurysm, arteriovenous malformation, moyamoya disease, etc.)
- •14. When the researchers determine that participation in the the present study is not suitable based on medical findings, etc.
研究者
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