Swallowing dysfunction in critically ill patients

Not Applicable

• Conditions: Health Condition 1: G729- Myopathy, unspecified

• Registration Number: CTRI/2023/05/052723
• Lead Sponsor: CCM department

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Age > 18 years

2.48 hours to 96 hours post extubation after prolonged intubation

3.All tracheostomized patients who are already on oral feeds or in whom initiation of oral feeds is planned

4.Conscious and able to follow verbal commands [GCS at least E4 VT M6 (10T)]

5. Hemodynamically stable patients

Exclusion Criteria

1. Presence of pre-existing dysphagia

2. Severe agitation and possible inability to

cooperate with the examination

3. Bilateral obstruction of the nasal passages

4.Pre-existing neurological conditions, such as

stroke and neuromuscular disease like myasthenia gravis, Lambert-Eaton myasthenic syndrome [LEMS]

5. Conditions affecting anatomic structures of the swallowing tract

6.History of recent trauma to the nasal cavity or surrounding tissue

7. Recent MI < 1month

8. Pre-existing congestive heart failure

9. Cardiac disorder with acute risk of vasovagal episode and bradycardia

10. Severe bleeding disorders and/or recent severe epistaxis (nosebleed)

11. Requiring oxygen more than 5lt/min

12.Recent trans-oesophageal echocardiography

13. Head and neck or oropharyngeal cancer

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To identify the prevalence of swallowing dysfunction in post extubated and <br/ ><br>tracheostomised patients without pre-existing dysphagia <br/ ><br>2. To identify the risk factors associated with the development of dysphagia <br/ ><br>3. To correlate between the severity of dysphagia and the its effects on patient outcomes <br/ ><br>Timepoint: At the time of bronchoscopic assessment of swallowing

Secondary Outcome Measures

Name	Time	Method
â?¢Need for reintubation, development of hospital-acquired pneumonia (HAP) <br/ ><br>â?¢Incidence of in-hospital mortality <br/ ><br>â?¢Length of ICU and hospital stay <br/ ><br>â?¢Patients discharged with feeding tube <br/ ><br>Timepoint: From the day of test to day of discharge or death