Risk/benefit ratio of polyphenols and ethanol contained in red wine

Not Applicable

Completed

• Conditions: Arteriosclerosis; Circulatory System; Chronic ischaemic heart disease

• Registration Number: ISRCTN88720134
• Lead Sponsor: Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación [MICINN]) (Spain)

Brief Summary

2012 gut microbiota results in https://pubmed.ncbi.nlm.nih.gov/22552027/ (added 30/12/2020) 2012 atherosclerosis marker results in https://pubmed.ncbi.nlm.nih.gov/22205309/ (added 30/12/2020) 2012 blood pressure results in https://pubmed.ncbi.nlm.nih.gov/22205309/ (added 30/12/2020) 2013 glucose and lipid metabolism results in https://pubmed.ncbi.nlm.nih.gov/22999066/ (added 30/12/2020) 2013 LPS results in https://pubmed.ncbi.nlm.nih.gov/23576043/ (added 30/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-05-14
• Study Completion: 2010-01-01
• Last Update Posted: 11 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 67

Inclusion Criteria

1. Males between 55 and 80 years old
2. No documented cardiovascular disease (ischaemic heart disease - angina or recent or old myocardial infarction or previous or cerebral vascular accident, peripheral vascular disease)
3. Have diabetes mellitus or three or more of the following factors:
3.1. Current smoking
3.2. Hypertension
3.3. Hypercholesterolaemia (low density lipoprotein [LDL]-cholesterol greater than 160 mg/dl)
3.4. High density lipoprotein (HDL)-cholesterol less than 40 mg/dl
3.5. Overweight or obese (body mass index greater than 25 kg/m^2)
3.6. Family history of premature coronary heart disease
4. Participant gives signed informed consent

Exclusion Criteria

Current exclusion criteria as of 23/05/2012
1. Previous history of cardiovascular disease (ischaemic heart disease - angina or recent or old myocardial infarction, cerebral vascular accident, or peripheral vascular disease)
2. Any severe chronic disease
3. Alcoholism
4. Other toxic abuse
5. Human immunodeficiency virus infection
6. Malnutrition
7. Acute infectious diseases
8. Customary use of vitamin supplements

Previous exclusion criteria
1. Previous history of cardiovascular disease (ischaemic heart disease - angina or recent or old myocardial infarction, cerebral vascular accident, or peripheral vascular disease)
2. Any severe chronic disease
3. Alcoholism
4. Other toxic abuse

Study & Design

• Study Type: Interventional
• Study Design: Not specified