The effect of curcuma longa on insulin resistance in PCOS patients: a randomized controlled trial
- Conditions
- polycystic ovary syndrome
- Registration Number
- ITMCTR1900002384
- Lead Sponsor
- Chongqing Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
(1) Complying with the diagnostic criteria of polycystic ovary syndrome recommended by the European Society of Human Reproductive and Embryonic Medicine (ESHRE/ASRM) in Rotterdam in 2003;
(2) Aged 18-60 years old;
(3) No desire for pregnancy, non-drug contraceptive measures (male using condom) were adopted after selection.
(1) Long-term or recent exogenous androgen users or those receiving steroid corticosteroid therapy, or those receiving malignant tumors, or those who have a history of drug abuse and alcoholism in the past two years;
(2) Those who have used metformin or other insulin sensitizers in the past month;
(3) Complicated with other endocrine diseases, such as hyperprolactinemia, thyroid disease, androgen-secreting tumors, Cushing's syndrome, congenital adrenocortical hyperplasia and 21-hydroxylase deficiency atypical adrenocortical hyperplasia (17-hydroxyprogen level was measured).
(4) Those with serious cardiovascular, blood, liver and kidney diseases and low immune function; those with ALT or AST higher than the upper limit of normal reference value and serum creatinine higher than the upper limit of normal reference value;
(5) Patients who cannot take effective contraceptive measures in the course of the experiment;
(6) Pregnant women and lactating women.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HOMA-IR;
- Secondary Outcome Measures
Name Time Method Weight, waist circumference; Blood sugar and insulin; Blood lipid profile; Sex hormones;