ISRCTN82767023已完成未知
Randomized comparison of surveillance intervals in Familial Colorectal Cancer: The Dutch FAmilial ColorecTal cancer Surveillance study (the FACTS study) Group
eiden University Medical Center0 个研究点目标入组 528 人开始时间: 2014年12月5日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 528
研究概览
简要总结
2015 results in https://www.ncbi.nlm.nih.gov/pubmed/26527788 (added 05/03/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Individuals aged between 45 and 65 years,
- •2. A positive family history for colorectal cancer (CRC), i.e., one first-degree relative (FDR) diagnosed with CRC <50 years, or two FDRs diagnosed with CRC at any age.
- •Subjects were excluded if they had 3 or more adenomas at baseline colonoscopy, while those with 0-2 adenomas were randomized into two groups: A) colonoscopy at 6 years and B) colonoscopy at 3 and 6 years.
排除标准
- •1. Additional first or second-degree relatives with CRC
- •2. A personal history of inflammatory bowel disease
- •3. Previous colorectal surgery,
- •4. A first-degree relative with CRC with known microsatellite instability or strong suspicion of Lynch syndrome (e.g., combination of CRC and endometrial cancer).
研究者
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