NCT06356051已完成不适用
Evaluation of Cardiovascular Disease Risk in Children With Type 1 Diabetes Mellitus by Oscillometric Method and Echocardiography
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 202
- 试验地点
- 1
- 主要终点
- Epicardial fat thickness
研究概览
简要总结
Epicardial fat thickness, carotid intima-media thickness, and augmentation index from arterial stiffness indicators are increased in children with T1DM compared to the healthy control group. These results support the idea that children with T1DM present significant changes in important subclinical indicators for the development of cardiovascular disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 8 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •type T1DM patients
- •body mass index (BMI) between the 5th and 85th percentile according to age and gender
- •having T1DM for at least 2 years
- •ages 8-18 years
排除标准
- •having any chronic diseases other than T1DM
- •presence of a congenital and/or acquired heart disease, hypertension etc.
结局指标
主要结局
Epicardial fat thickness
时间窗: january 2023-june 2023
Epicardial fat thickness was measured with Echocardiography as milimeter. Epicardial fat was identified as the echo-free space between the outer wall of the myocardium and the visceral layer of pericardium. The values of children with type 1 DM were compared with healthy children. Values are given as mean and standard deviation.
次要结局
- arterial stiffness parameters such as pulse wave velocity, augmentation index(january 2023-june 2023)
- carotid intima-media thickness(january 2023-june 2023)
研究者
研究点 (1)
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