Recovery of Quality of Life After Cytoreductive Surgery and Intraperitoneal Chemotherapy for Colorectal Cancer and Pseudomyxoma Peritonei
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Brief pain inventory (BPI)
研究概览
简要总结
Cytoreductive surgery with intraperitoneal chemotherapy is one of the most important treatments for patients with colorectal cancer and peritoneal metastasis. For the best survival rates, complete removal of all metastatic lesions is the most important part of treatment, and various surgical procedures are required for the complete cytoreduction. Therefore, the postoperative morbidity rates are higher than those of localized colon cancer surgeries and patients can experience a prolonged recovery period and deterioration of physical activities over a long period. The aim of this study is to investigate the change of quality of life after cytoreductive surgery and intraperitoneal chemotherapy for colorectal cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Colorectal cancer peritoneal metastasis
- •Pseudomyxoma peritonei
- •ECOG (Eastern Cooperative Oncology Group) performance status 0-3
- •Normal bone marrow, kidney, and liver function
- •Patient must sign and date the informed consent
排除标准
- •Palliative surgery
- •Palliative intraperitoneal chemotherapy
- •Psychotic disorder
- •Drug abuser
结局指标
主要结局
Brief pain inventory (BPI)
时间窗: Changes from baseline pain scores at postoperative 12 months
Pain recovery after cytoreductive surgery and intraperitoneal chemotherapy
次要结局
- European Organisation for Research and Treatment of Cancer (EORTC) Quality of life questionnaire (QLQ)-C30(preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months)
- EORTC QLQ for colorectal cancer(preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months)
- Postoperative recovery(150 days after surgery)
- Short-form(SF)-36(preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months)
- Postoperative morbidity(90 days after surgery)
- Postoperative mortality(90 days after surgery)
- Brief pain inventory (BPI)(preoperative, postoperative 3 months, postoperative 6 months, postoperative 24 months)
研究者
Soo Yeun Park
Principal investigator
Kyungpook National University Hospital