Quality of Life After Cytoreductive Surgery and Intraperitoneal Chemotherapy
- Conditions
- Colorectal Cancer Metastatic
- Registration Number
- NCT03503071
- Lead Sponsor
- Kyungpook National University Hospital
- Brief Summary
Cytoreductive surgery with intraperitoneal chemotherapy is one of the most important treatments for patients with colorectal cancer and peritoneal metastasis. For the best survival rates, complete removal of all metastatic lesions is the most important part of treatment, and various surgical procedures are required for the complete cytoreduction. Therefore, the postoperative morbidity rates are higher than those of localized colon cancer surgeries and patients can experience a prolonged recovery period and deterioration of physical activities over a long period. The aim of this study is to investigate the change of quality of life after cytoreductive surgery and intraperitoneal chemotherapy for colorectal cancer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 50
- Colorectal cancer peritoneal metastasis
- Pseudomyxoma peritonei
- ECOG (Eastern Cooperative Oncology Group) performance status 0-3
- Normal bone marrow, kidney, and liver function
- Patient must sign and date the informed consent
- Palliative surgery
- Palliative intraperitoneal chemotherapy
- Psychotic disorder
- Drug abuser
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brief pain inventory (BPI) Changes from baseline pain scores at postoperative 12 months Pain recovery after cytoreductive surgery and intraperitoneal chemotherapy
- Secondary Outcome Measures
Name Time Method European Organisation for Research and Treatment of Cancer (EORTC) Quality of life questionnaire (QLQ)-C30 preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months Qualify of life questionnaire for cancer patients
EORTC QLQ for colorectal cancer preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months Quality of life questionnaire for patients with colorectal cancer
Short-form(SF)-36 preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months Global measure of health-related quality of life
Postoperative morbidity 90 days after surgery Incidence and degree of surgical and medical complications after surgery
Postoperative mortality 90 days after surgery Incidence of postoperative mortality
Brief pain inventory (BPI) preoperative, postoperative 3 months, postoperative 6 months, postoperative 24 months Pain recovery after cytoreductive surgery and intraperitoneal chemotherapy
Postoperative recovery 150 days after surgery Duration of hospital stay after surgery
Trial Locations
- Locations (1)
Kyungpook National University Chilgok Hospital
🇰🇷Daegu, Korea, Republic of