PHYSIO+++ PHYSIOtherapy management for hypoxaemia following abdominal surgery: Talk + Walk + Breathe + Non-Invasive Ventilation. A pilot feasibility randomised controlled trial.

Metro South Health0 个研究点目标入组 50 人开始时间: 2022年6月15日最近更新: 2024年9月2日

适应症

试验速览

Results are not yet available

•Major elective or non-elective abdominal surgery (open abdominal incision >5cm, or when anesthetic time >3 hours: laparoscopy or robotic surgery to the abdomen), extubated within 24hrs of surgery, age greater than or equal to 18 years, hypoxaemia while self-ventilating via a natural airway at least 3 hours after extubation and within 72 hours following abdominal surgery. Hypoxaemia is defined by a positive Air Test 90 (oxyhaemoglobin saturations <90% within 2 minutes of breathing room air) or if the Air Test 90 is not able to be conducted, a ratio of partial pressure of oxygen to fraction of inspired oxygen <300, where an arterial blood gas is available.

•Unable to collaborate due to language or severe cognitive impairment, pregnancy, oesophagectomy, tracheostomy, previously participated in PHYSIO+++, current enrolment in a trial with similar therapies or outcomes, patients managed under airborne or droplet precautions, preoperative muscle weakness necessitating assistance to cough (for example a neuromuscular disorder or spinal cord injury), refusal to participate, not able to be recruited within 8 hours of screening as eligible, and those who do not receive medical clearance to participate in the trial due to (a) imminent (anticipated within 12hours of study inclusion) surgery, palliation, reintubation or the need for continuous medically prescribed NIV/CPAP (b) profound respiratory failure or cardiovascular instability (c) NIV contraindicated.

发起方

Metro South Health