Measurement of the Oxygen Saturation in the Retinal Vessels With Oxymap
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chorioretinal Disorders in Diseases Classified Elsewhere
- Sponsor
- Kagawa University
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Change of retinal oxygen saturation from baseline at 6 months
- Last Updated
- 8 years ago
Overview
Brief Summary
Retinal oximetry can be measured with newly developed Oxymap (Oxymap ehf, Reykjavik, Iceland). Briefly, the device simultaneously acquires digital images at two wavelengths and automatically tracks retinal vessels on both images. Retinal vessel oxygen saturation is estimated by spectrophotometric analysis of light reflected from retinal vessels and from the immediately surrounding retina. Oxygen saturation measurements are made on major temporal arteries and veins. Briefly, the first and second degree vessels are used, with the addition of third degree vessels in images where peripapillary haemorrhage prevented analysis close to the optic disc. Vessel segments chosen for analysis are used consistently for consecutive measurements in the same retina.
Detailed Description
Retinal oximetry can be measured with newly developed Oxymap (Oxymap ehf, Reykjavik, Iceland). Briefly, the device simultaneously acquires digital images at two wavelengths and automatically tracks retinal vessels on both images. Retinal vessel oxygen saturation is estimated by spectrophotometric analysis of light reflected from retinal vessels and from the immediately surrounding retina. Oxygen saturation measurements are made on major temporal arteries and veins. Briefly, the first and second degree vessels are used, with the addition of third degree vessels in images where peripapillary haemorrhage prevented analysis close to the optic disc. Vessel segments chosen for analysis are used consistently for consecutive measurements in the same retina. Retinal oximetry in various chorioretinal diseases will be measured with Oxymap.
Investigators
Akitaka Tsujikawa
Professor and Chairman
Kagawa University
Eligibility Criteria
Inclusion Criteria
- •Healthy eyes and eyes with various chorioretinal diseases, including diabetic retinopathy, retinal vein occlusion, epiretinal membrane, macular hole, inherited chorioretinal diseases, glaucoma, retinal detachment, etc.
Exclusion Criteria
- •Eye with medial opacity.
Outcomes
Primary Outcomes
Change of retinal oxygen saturation from baseline at 6 months
Time Frame: Six months.