An effect of hormone replacement therapy on cataract and glaucoma in postmenopausal women.

Not Applicable

Completed

• Conditions: Cataract and glaucoma; Eye Diseases

• Registration Number: ISRCTN72439325
• Lead Sponsor: Bucheon St. Mary's Hospital (South Korea)

Brief Summary

2015 results presemted at ARVO in https://iovs.arvojournals.org/article.aspx?articleid=2333383 (added 10/05/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-03-01
• Study Start: 2014-06-18
• Last Update Posted: 24 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 264

Inclusion Criteria

Eligible patients included postmenopausal women at least 5 years of postmenopausal period, who either:
1. Never used HRT (Group 1: 128 patients) after menopause
2. Continuously used HRT (Group 2: 136 patients) for more 5 years from menopause

Exclusion Criteria

1. A history of any ocular injury or disorder
2. An infection, inflammation, surgery within the prior 6 months
3. Any uncontrolled systemic disease, or significant illness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cortical, nuclear, and posterior subcapsular density, pentacam nucleus staging (PNS), pentacam densitometry of zone (PDZ) measured by pentacam.

Secondary Outcome Measures

Name	Time	Method
Antioxidant and inflammatory cytokines activities in serum.