NCT04867863已完成不适用
SCREENING OF CELIAC DISEASE IN SCHOLAR CHILDREN IN ITALY
Università Politecnica delle Marche1 个研究点 分布在 1 个国家目标入组 4,570 人开始时间: 2015年5月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 4,570
- 试验地点
- 1
- 主要终点
- prevalence of celiac serology in children aged 5-10
研究概览
简要总结
The main aim of the study is to currently define the prevalence of celiac disease (CD) in children aged 5-10 years in 2 Italian cities (Ancona and Verona). The screening protocol is based on a 1st line genetic test (searche of HLA DQ2/DQ8 genotypes) followed by a serological diagnosis (IgA TTG and IgG DGP).
详细描述
All scholar children aged 5-10 years living in the cities of Ancona and Verona will be invited to partecipate. Children enrolled will be investigated as follows:
- HLA DQ2/DQ8 genotyping (by a rapid test)
- In children genetically predisposed to CD serological investigations will be performed (both IgA TTG and IgG DGP antibodies)
- The overall population will be evaluated for the prevalence and severity of dental caries (by using the DMFT/dmft index)
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •celiac disease, on a gluten free diet
结局指标
主要结局
prevalence of celiac serology in children aged 5-10
时间窗: 2 years
次要结局
- prevalence of dental caries in children genetically predisposed to CD in comparison with children not predisposed(2 years)
研究者
Carlo Catassi, M.D.
PROFESSOR OF PEDIATRICS AND HEAD OF THE DEPARTMENT OF PEDIATRICS, UNIVERSITA POLITECNICA DELLE MARCHE
Università Politecnica delle Marche
研究点 (1)
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