Acute Salt Sensitivity of Blood Pressure
Not Applicable
Completed
- Conditions
- Blood Pressure
- Interventions
- Dietary Supplement: dietary salt
- Registration Number
- NCT04844255
- Lead Sponsor
- Mulungushi University
- Brief Summary
Dietary salt raises blood pressure in certain individuals immediately after ingestion (acute salt sensitivity; ASS) while not affecting others. It is hypothesized that ASS is a risk factor for hypertension. However, no thresholds or diagnostic guideline is available for ASS. This study is the first aim in the main study (HIPO CAP DITSH Study) aimed at determining the threshold or blood pressure cut-offs for ASS upon ingesting dietary salt.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
- Adults aged 18 years and above. Normotensive. If Hypertensive (should be off antihypertensive medication at least 2 weeks prior to the study)
Exclusion Criteria
- diabetes patients, ill participants
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Pre and post intervention group dietary salt Same individuals are examined before and after taking 2 tablets of salt
- Primary Outcome Measures
Name Time Method Acute salt sensitivity 160 minutes Mean arterial pressure change of 10 mmHg
- Secondary Outcome Measures
Name Time Method Systolic blood pressure change 160 minutes Systolic blood pressure change of equal to or more than 20 mmHg
Diastolic blood pressure change 160 minutes Diastolic blood pressure change of equal to or more than 10 mmHg
Trial Locations
- Locations (1)
Livingstone Central Hospital
🇿🇲Livingstone, Southern, Zambia